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KMID : 0903519960390040265
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1996 Volume.39 No. 4 p.265 ~ p.267
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Isolation and Characterization of 4 - hydroxycinnamic Acid with Antimicrobial Activity from Aralia elata
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Abstract
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The methanol extracts of Aralia elata showed antimicrobial activity against bacteria. The antimicrobial active principle was successively purified with solvent fractionation, silica gel adsorption column chromatography, Sephadex LH-20 column chromatography, silica gel partition column chromatography and HPLC. The active substance was isolated by HPLC on C_(18) column with an acetic acid-MeOH system. The active substance was identified as trans-4-hydroxycinnamic acid by MS, ¹H-NMR and ^(13)C-NMR.
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